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Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk

Complex-Trait Prediction in the Era of Big Data
Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections

A novel gene-diet pair modulates C. elegans aging
E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo

ISSUE HIGHLIGHTS [Issue Highlights]
Developmental Bias and Evolution: A Regulatory Network Perspective [Perspectives]

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